Living EuroGuiDerm Guideline for the systemic treatment of Atopic Eczema

Download entire guideline document in the latest version (April 2026): 

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9700

Last updated
Updated 2026
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Introduction, scoping, population and targeted users
06/2022
Original version
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835
Treatment and treatment goals definitions
06/2022
Original version
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1077
Methods Section
01/2026
New information on update
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426
Treatment algorithm (adults + children/adolescents)
01/2026
New voting on the level of systemic treatment
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2328
Overview tables
01/2026
New voting on systemic treatment
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908
Implementation slidekit
01/2026
Slides with updated and new recommendations, updated treatment algorithms and updated overview tables
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689

Last updated
Updated 2026
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Basic emollients and moisturizers
06/2022
Original version
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1238
Antiinflammatory treatment
06/2022
Original version
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1270
Antimicrobial treatment
06/2022
Original version
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395

Last updated
Updated 2026
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Antipruritic treatment
06/2022
Original version
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617

Last updated
Updated 2026
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Phototherapy and photochemotherapy
06/2022
Original version
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352

Last updated
Updated 2026
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Introduction to systemic treatment
01/2026
New guidance on vaccination, treatment switching, adaption of frequency and interval
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1271
Azathioprine
01/2026
Deletion of the recommendation; minor adjustments to the background text
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318
Ciclosporin
01/2026
New voting; minor adjustments to the background text
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556
Systemic glucocorticosteroids
01/2026
New voting; minor adjustments to the background text
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259
Methotrexate
01/2026
New voting; minor adjustments to the background text
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384
Dupilumab
01/2026
New voting; minor adjustments to the background text
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1136
Lebrikizumab
01/2026
New voting; minor adjustments to the background text
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518
Nemolizumab
01/2026
New voting; minor adjustments to the background text
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367
Tralokinumab
01/2026
New voting; minor adjustments to the background text
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629
JAK-Inhibitors introduction
01/2026
Minor adjustments to the background text
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289
Abrocitinib
01/2026
New voting; minor adjustments to the background text
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725
Baricitinib
01/2026
New voting; minor adjustments to the background text
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573
Upadacitinib
04/2026
New voting; minor adjustments to the background text; clarification
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800
Other systemic treatment
01/2026
Deletion of alitretinoin recommendation; adjustments to the background text
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326
Therapies that were used in past
01/2026
MMF added; omalizumab added
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188

Last updated
Updated 2026
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Patient's perspective
06/2022
Original version
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176
Avoidance techniques in atopic eczema
06/2022
Original version
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169
Dietary interventions in atopic eczema
06/2022
Original version
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284
Allergen-specific immunotherapy
06/2022
Original version
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106
Complementary medicine
06/2022
Original version
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142
Psychological and educational interventions
06/2022
Original version
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123
Occupational aspects
06/2022
Original version
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97

Last updated
Updated 2026
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Pregnancy, breastfeeding, wish for child
01/2026
Updated recommendations and background text
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467
Considerations for paediatric and adolescent patients
06/2022
Original version
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386

Last updated
Updated 2026
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Strengths and limitations
06/2022
Original version
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107
Methods Report
12/2025
New information on update
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237
Evidence Report
04/2025
Updated evidence
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308
Guideline
Previous guideline 2018
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1181

Last updated
Updated 2026
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Appendix: Antimicrobial treatment
10/2022
Original version
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100
Appendix: Phototherapy and Photochemotherapy
10/2022
Original version
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70

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