Living EuroGuiDerm Guideline for the systemic treatment of Atopic Eczema

Download entire guideline document in the latest version (September 2023, partial update February 2025): 

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9596

Last updated
Updated 2025
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Introduction, scoping, population and targeted users
06/2022
Original version
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751
Treatment and treatment goals definitions
06/2022
Original version
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988
Methods Section
03/2025
New information on update
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382
Treatment algorithm (adults + children/adolescents)
02/2025
Lebrikizumab added; approval extension for baricitinib and abrocitinib added to the plan for children/adolescents
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2117
Overview tables
03/2025
Lebrikizumab dose, baricitinib children/adolescents dose and abrocitinib adolescents dose added
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821
Implementation slidekit
03/2025
Slides with updated and new recommendations, updated treatment algorithms and updated overview tables
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629

Last updated
Updated 2025
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Basic emollients and moisturizers
06/2022
Original version
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1044
Antiinflammatory treatment
06/2022
Original version
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1071
Antimicrobial treatment
06/2022
Original version
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329

Last updated
Updated 2025
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Antipruritic treatment
06/2022
Original version
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531

Last updated
Updated 2025
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Phototherapy and photochemotherapy
06/2022
Original version
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297

Last updated
Updated 2025
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Introduction to systemic treatment
03/2025
Minor adjustments to the background text
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1131
Azathioprine
02/2025
Minor adjustments to the background text
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267
Ciclosporin
02/2025
Minor adjustments to the background text
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467
Systemic glucocorticosteroids
02/2025
Minor adjustments to the background text
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202
Methotrexate
03/2025
Minor adjustments to the background text
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323
Dupilumab
02/2025
Minor adjustments to the background text
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1012
Lebrikizumab
02/2025
New recommendation and updated background text
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462
Nemolizumab
02/2025
Updated background text
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292
Tralokinumab
03/2025
Minor adjustments to the background text
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589
JAK-Inhibitors introduction
03/2025
Minor adjustments to the background text
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204
Abrocitinib
02/2025
Updated background text
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675
Baricitinib
03/2025
Updated background text
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522
Upadacitinib
03/2025
Minor adjustments to the background text
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732
Other systemic treatment
10/2022
Updated recommendation
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280
Therapies that were used in past
06/2022
Original version
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160

Last updated
Updated 2025
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Patient's perspective
06/2022
Original version
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151
Avoidance techniques in atopic eczema
06/2022
Original version
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139
Dietary interventions in atopic eczema
06/2022
Original version
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231
Allergen-specific immunotherapy
06/2022
Original version
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79
Complementary medicine
06/2022
Original version
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115
Psychological and educational interventions
06/2022
Original version
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101
Occupational aspects
06/2022
Original version
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77

Last updated
Updated 2025
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Pregnancy, breastfeeding, wish for child
03/2025
Updated recommendations and background text
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386
Considerations for paediatric and adolescent patients
06/2022
Original version
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322

Last updated
Updated 2025
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Strengths and limitations
06/2022
Original version
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90
Methods Report
12/2025
New information on update
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212
Evidence Report
04/2025
Updated evidence
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282
Guideline
Previous guideline 2018
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1142

Last updated
Updated 2025
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Appendix: Antimicrobial treatment
10/2022
Original version
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81
Appendix: Phototherapy and Photochemotherapy
10/2022
Original version
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52

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