Living EuroGuiDerm Guideline for the systemic treatment of psoriasis vulgaris

 

The general recommendations developed in this guideline are based on the Living Cochrane review (https://pubmed.ncbi.nlm.nih.gov/35603936/). With new evidence and new results becoming available, the guideline development group will consider these and decide if and when an update is necessary. This will also be the case for the recommendations for specific clinical and comorbid situations.

 

 

Download entire guideline document in the latest version (September 2023, partial update February 2025): 

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9514

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Introduction, scoping, population and targeted users
09/2023
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618
Disease severity and treatment goals
09/2023
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1134
Methods and evidence section
02/2025
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304
Main Recommendations and Decision Grid
02/2025
Pregnancy changes were added
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1572
Implementation slides
02/2025
New data added
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581
IFPA Guideline
09/2023
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599

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Acitretin
03/2023
No changes, minor editorial changes in 2025
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481
Ciclosporin
03/2023
Reference added
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408
Fumarates
03/2023
No changes
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183
Methotrexate
03/2023
New data added, pregnancy changes were added in 2025
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698
Adalimumab
03/2023
No changes, minor editorial changes in 2025
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335
Apremilast
03/2023
New data added
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394
Bimekizumab
09/2023
New data added
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296
Brodalumab
09/2023
New data added
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129
Certolizumab – Pegol
09/2023
No changes, minor editorial changes in 2025
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140
Deucravacitinib
02/2025
Recommendation concerning laboratory controls updated
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319
Etanercept
03/2023
No changes
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97
Guselkumab
03/2023
No changes
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270
Infliximab
03/2023
No changes, minor editorial changes in 2025
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128
Ixekizumab
09/2023
New data added
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207
Risankizumab
09/2023
New data added
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352
Secukinumab
09/2023
New data added
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223
Tildrakizumab
03/2023
No changes
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169
Ustekinumab
03/2023
No changes
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170
Biosimilars
09/2023
New data added, minor changes in 2025
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139
Newly approved medications and treatments in the pipeline
10/2021
No changes
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289

Last updated
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Psoriatic arthritis
03/2023
New data added, recommendations changed
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515
Inflammatory bowel disease
10/2021
Recommendation concerning bimekizumab added
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209
Cancer
09/2023
New data added, minor changes in 2025
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587
Depression
09/2023
New data added, minor editorial changes in 2025
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154
Diabetes Mellitus
09/2023
New data added, recommendations changed, minor changes in 2025
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231
Heart disease
03/2023
New data added, minor editorial changes in 2025
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279
Kidney disease
03/2023
New data added
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144
Neurological diseases
09/2023
New data added, minor editorial changes in 2025
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171
Viral Hepatitis
02/2025
New data added, recommendations changed
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235
Tuberculosis: Screening
09/2023
Editorial changes, minor editorial changes in 2025
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245
Tuberculosis: Treatment
09/2023
Editorial changes, minor editorial changes in 2025
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252
Wish for child / Pregnancy
02/2025
New data added, recommendations changed
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450
Vaccinations
03/2023
Completely new written
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306
Inmunogenicity
10/2021
No changes
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124

Last updated
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Methods Report
02/2025
Editorial changes
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243
Strength and limitations
09/2023
No changes
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83
Abbreviations
09/2023
Editorial changes
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39